37 research outputs found
Active Analytics: Suggesting Navigational Links to Users Based on Temporal Analytics Data
Front-end developers are tasked with keeping websites up-to-date while optimizing user experiences and interactions. Tools and systems have been developed to give these individuals granular analytic insight into who, with what, and how users are interacting with their sites. These systems maintain a historical record of user interactions that can be leveraged for design decisions. Developing a framework to aggregate those historical usage records and using it to anticipate user interactions on a webpage could automate the task of optimizing web pages. In this research a system called Active Analytics was created that takes Google Analytics historical usage data and provides a dynamic front-end system for automatically updating web page navigational elements. The previous year’s data is extracted from Google Analytics and transformed into a summarization of top navigation steps. Once stored, a responsive front-end system selects from this data a timespan of three weeks from the previous year: current, previous and next. The most frequently reached pages, or their parent pages, will have their navigational UI elements highlighted on a top-level or landing page to attempt to reduce the effort to reach those pages. The Active Analytics framework was evaluated by eliciting volunteers by randomly assigning two versions of a site, one with the framework, one without. It was found that users of the framework-enabled site were able to navigate a site more easily than the original
Emergent diversity in an open-ended evolving virtual community
Understanding the dynamics of biodiversity has
become an important line of research in theoretical ecology and,
in particular, conservation biology. However, studying the evolution
of ecological communities under traditional modeling approaches
based on differential calculus requires speciesʼ characteristics to be
predefined, which limits the generality of the results. An alternative
but less standardized methodology relies on intensive computer
simulation of evolving communities made of simple, explicitly
described individuals. We study here the formation, evolution, and
diversity dynamics of a community of virtual plants with a novel
individual-centered model involving three different scales: the
genetic, the developmental, and the physiological scales. It constitutes
an original attempt at combining development, evolution, and
population dynamics (based on multi-agent interactions) into one
comprehensive, yet simple model. In this world, we observe that our
simulated plants evolve increasingly elaborate canopies, which are
capable of intercepting ever greater amounts of light. Generated
morphologies vary from the simplest one-branch structure of
promoter plants to a complex arborization of several hundred
thousand branches in highly evolved variants. On the population
scale, the heterogeneous spatial structuration of the plant community
at each generation depends solely on the evolution of its component
plants. Using this virtual data, the morphologies and the dynamics
of diversity production were analyzed by various statistical methods,
based on genotypic and phenotypic distance metrics. The results
demonstrate that diversity can spontaneously emerge in a community
of mutually interacting individuals under the influence of specific
environmental conditions.This research
was partially supported by a grant for the GENEX project (P09-TIC-5123) from the Consejería de
Innovación y Ciencia de Andalucía. J.D.F. was supported by a FPU grant from the Spanish Ministerio
de Educación. R.D. wishes to thank the Région Ile-de-France for supporting his research position at
the Complex Systems Institute, Paris Ile-de-France
UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity
Background The uncoupling protein 1 (UCP1) is a hallmark of brown adipocytes and pivotal for cold- and diet-induced thermogenesis. Methodology/Principal Findings Here we report that cyclooxygenase (COX) activity and prostaglandin E2 (PGE2) are crucially involved in induction of UCP1 expression in inguinal white adipocytes, but not in classic interscapular brown adipocytes. Cold-induced expression of UCP1 in inguinal white adipocytes was repressed in COX2 knockout (KO) mice and by administration of the COX inhibitor indomethacin in wild-type mice. Indomethacin repressed β-adrenergic induction of UCP1 expression in primary inguinal adipocytes. The use of PGE2 receptor antagonists implicated EP4 as a main PGE2 receptor, and injection of the stable PGE2 analog (EP3/4 agonist) 16,16 dm PGE2 induced UCP1 expression in inguinal white adipose tissue. Inhibition of COX activity attenuated diet-induced UCP1 expression and increased energy efficiency and adipose tissue mass in obesity-resistant mice kept at thermoneutrality. Conclusions/Significance Our findings provide evidence that induction of UCP1 expression in white adipose tissue, but not in classic interscapular brown adipose tissue is dependent on cyclooxygenase activity. Our results indicate that cyclooxygenase-dependent induction of UCP1 expression in white adipose tissues is important for diet-induced thermogenesis providing support for a surprising role of COX activity in the control of energy balance and obesity development
2017 Research & Innovation Day Program
A one day showcase of applied research, social innovation, scholarship projects and activities.https://first.fanshawec.ca/cri_cripublications/1004/thumbnail.jp
Visualizing Tree Structures in Genetic Programming
This paper presents methods to visualize the structure of trees that occur in genetic programming. These methods allow for the inspection of structure of entire trees even though several thousands of nodes may be involved. The methods also scale to allow for the inspection of structure for entire populations and for complete trials even though millions of nodes may be involved. Examples are given that demonstrate how this new way of “seeing” can afford a potentially rich way of understanding dynamics that underpin genetic programming. The examples indicate further studies that might be enabled by visualizing structure at these scales.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45620/1/10710_2005_Article_7621.pd
Generative Representations for Evolving Families of Designs
Since typical evolutionary design systems encode only a single artifact with each individual, each time the objective changes a new set of individuals must be evolved. When this objective varies in a way that can be parameterized, a more general method is to use a representation in which a single individual encodes an entire class of artifacts. In addition to saving time by preventing the need for multiple evolutionary runs, the evolution of parameter-controlled designs can create families of artifacts with the same style and a reuse of parts between members of the family. In this paper an evolutionary design system is described which uses a generative representation to encode families of designs. Because a generative representation is an algorithmic encoding of a design, its input parameters are a way to control aspects of the design it generates. By evaluating individuals multiple times with dierent input parameters the evolutionary design system creates individuals in which the input parameter controls speci c aspects of a design. This system is demonstrated on two design substrates: neural-networks which solve the 3/5/7-parity problem and three-dimensional tables of varying heights
Dynamics of heparan sulfate explored by neutron scattering.
International audienceThe temperature dependence of atomic fluctuations in heparan sulfate was measured for different time-scales between the picosecond and the nanosecond. The data established the role of hydration for the emergence of high-amplitude motions at 200-240 K, and the higher resilience of the polysaccharide compared to proteins measured under similar conditions